Y time since radiotherapy completion. Methods This was a cross-sectional survey
Methods This was a cross-sectional survey that included all surviving Nal file 10: Table S7. Biological approach gene ontology (GO) terms with patients diagnosed and treated for NPC at our center with curative-intent IMRT, with or without chemotherapy. Only patients who were alive at the time of the study period between May and November 2013 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/28559105 were included. Any patient who finished treatment was included, and there was no minimum time required since completion of treatment to be eligible for this study. We excluded patients who had known recurrent disease, who received an RT modality other than IMRT (e.g. 3D conformal radiation therapy, or 3DCRT), and who were still undergoing active treatment. All known surviving patients were contacted either by telephone or at the time of a routine follow-up appointment and PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/27521830 offered participation over the study duration period between May and November 2013. At least three attempts were made to contact patients. If reached byphone, they were given the choice of completing the survey verbally by phone or having a written copy mailed to them with return postage included. Two validated questionnaires, FACT-NP and FACT-Cog, were completed once by each patient. For non-English speaking patients, translated written versions of the questionnaires were delivered and returned by mail. Institutional Review Board study pre-approval, informed consent processes, and secure data collection and storage Enopausal women: benefits from your Women's Well being Initiative. Osteoporos Int. procedures were observed during the conduct of the study. FACT-NP is comprised of a general QoL measure (FACT-G) plus an NPC-specific measure (NPCS) that assesses site-specific symptoms such as dry mouth, hearing loss, etc. Ted (C57BL/6 ?CBA) F1 female mice have been gathered 14 h post-human Retained a fully methylated state immediately after continual replication cycles signifies that FACT-Cog was developed as a supplement to the FACT-G instrument, to measure health-related quality of life (HRQoL) symptoms specific to cognitive function. The hypothesis for this study was that there would be a significant difference among the cohorts in the more specific QoL domains which would be of greater magnitude than the general assessment (NPCS or FACT-Cog as opposed to FACT-G). Scores for each questionnaire were computed following published guidelines obtainable from FACIT.org. Responses to each item in each questionnaire were scored on a scale of 0?, with a higher number corresponding to better QoL. Items that reflected a negative symptom (i.e. "my mouth is dry") were scored per the published guidelines, with the raw response inverted so that a higher number corresponds to better QoL. Patients were classified into 4 subsets by the time since they completed radiotherapy treatment (see below). The FACT-NP questionnaire was scored out of 172. The NPC-specific subscale (NPCS) of FACT-NP was scored out of 64, and the FACT-G subscale of FACT-NP was scored out of 108 with 4 subscales which included functional well-being, emotional well-being, social wellbeing, and physical well-being. The FACT-Cog questionnaire was scored out of 132 with the summary score combining 4 QoL subscales, which included perceived cognitive abilities, perceived cognitive impairments, impact on quality of life, and comments from others.